Exosomes: roles, applications, and challenges in pharmaceutical industry
DOI:
https://doi.org/10.58342/MJ.V.3.I.1.3Keywords:
Exosomes, Drug delivery, Cancer therapy, Extracellular vesicles, Clinical applications, Nano-formulations, BiogenesisAbstract
Background and Objective: Exosomes, as nano-vesicles with the ability to transport molecules, have gained increasing importance in pharmaceutical sciences. The aim of this study is to investigate their structure, functions, applications, and clinical challenges.
Method: A systematic review of scientific literature was conducted. Recent valid articles published in databases such as PubMed, Scopus, and Google Scholar were searched and selected. Studies related to the structure, biogenesis, biological functions, diagnostic and therapeutic applications of exosomes, as well as methods of isolation, characterization, and their clinical challenges, were analyzed. In addition, existing reports on exosome-based formulations and clinical studies were reviewed, and the findings were summarized descriptively.
Findings: Exosomes demonstrated strong potential in targeted drug delivery, ability to cross biological barriers, and applications in diagnosis, cancer therapy, and vaccine development.
Conclusion: The findings indicate that exosomes, as natural nanocarriers, possess significant potential for drug delivery and clinical applications; however, addressing challenges related to production, stability, and standardization is essential for their broader use in medical practice.
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